Characteristics of kidney stones in women

Wilcox: Therapy in Nephrology & Hypertension, 3rd ed.
Copyright © 2008 Saunders, An Imprint of Elsevier
PART V – Nephrolithiasis
Chapter 35 – Evaluation and Management of Kidney Stone Disease
Eric N. Taylor, Gary C. Curhan
Symptomatic nephrolithiasis classically presents with sudden unilateral flank pain. The pain is caused by the passage of a kidney stone from the renal pelvis to the ureter and is due to ureteral spasm. The pain is often severe and can cause nausea and vomiting. The location of the pain depends on the location of the stone; a stone in the upper ureter may cause pain to radiate anteriorly to the abdomen, and a stone in the lower ureter can cause pain to radiate to the ipsilateral testicle in men or to the ipsilateral labium in women.

Cunningham et al.: Williams Obstetrics, 24th ed.
Copyright © 2014  The McGraw-Hill Companies, Inc.
Chapter 53. Renal and Urinary Tract Disorders
“There is some evidence that pregnant women may have fewer symptoms with stone passage because of urinary tract dilatation (Hendricks, 1991; Tan, 2013). That said, more than 90 percent of pregnant women with nephrolithiasis present with pain. Gross hematuria is less common than in nonpregnant women and was reported to be a presenting symptom in 23 percent of women described by Butler and associates (2000). In another study, however, Lewis and coworkers (2003) found that only 2 percent had hematuria.”

Reviewed and updated 4/24/2014 ldt

What is the recent evidence on whether closed catheter systems prevent catheter-associated bloodstream infections (CLABSIs)?

Ishizuka, Mitsuru, et al. “Needleless closed system does not reduce central venous catheter-related bloodstream infection: a retrospective study.” International surgery 98.1 (2013):88-93.

Newman, Nitza, et al. “Central venous catheter-associated bloodstream infections.” Pediatric blood & cancer 59.2 (2012):410-414.

Ellger, B, et al. “Non-return valves do not prevent backflow and bacterial contamination of intravenous infusions.” Journal of hospital infection 78.1 (2011):31-35.

Graves, Nicholas, Adrian GBarnett, and Victor DRosenthal. “Open versus closed IV infusion systems: a state based model to predict risk of catheter associated blood stream infections.” BMJ open 1.2 (2011):e000188-e000188.

Maki, Dennis G, et al. “Impact of switching from an open to a closed infusion system on rates of central line-associated bloodstream infection: a meta-analysis of time-sequence cohort studies in 4 countries.” Infection control and hospital epidemiology 32.1 (2011):50-58.

McAfee, Nancy, et al. “A continuous quality improvement project to decrease hemodialysis catheter infections in pediatric patients: use of a closed luer-lock access cap.” Nephrology Nursing Journal 37.5 (2010):541-4.

Jarvis, William R, et al. “Health care-associated bloodstream infections associated with negative- or positive-pressure or displacement mechanical valve needleless connectors.” Clinical infectious diseases 49.12 (2009):1821-1827.

Ishizuka, Mitsuru, et al. “Valve system does not reduce the catheter-related bloodstream infection.” Journal of investigative surgery 22.6 (2009):430-434.

Vilins, Margarete, et al. “Rate and time to develop first central line-associated bloodstream infections when comparing open and closed infusion containers in a Brazilian Hospital.” The Brazilian journal of infectious diseases 13.5 (2009):335-340.

Ivy, D D, et al. “Closed-hub systems with protected connections and the reduction of risk of catheter-related bloodstream infection in pediatric patients receiving intravenous prostanoid therapy for pulmonary hypertension.” Infection control and hospital epidemiology 30.9 (2009):823-829.

Franzetti, F, et al. “Impact on rates and time to first central vascular-associated bloodstream infection when switching from open to closed intravenous infusion containers in a hospital setting.” Epidemiology and Infection 137.7 (2009):1041-1048.

Blake, Molly. “Update: Catheter-related bloodstream infection rates in relation to clinical practice and needleless device type.” The Canadian journal of infection control 23.3 (2008):156-60, 162.

How should closed catheter systems be maintained?

Rupp, Mark E, et al. “Adequate disinfection of a split-septum needleless intravascular connector with a 5-second alcohol scrub.” Infection control and hospital epidemiology 33.7 (2012):661-665.
This is a prospective observational clinical survey and laboratory assessment of disinfection procedures.

Aly, Hany, et al. “Is bloodstream infection preventable among premature infants? A tale of two cities.” Pediatrics 115.6 (2005):1513-1518.
Described the protocol for maintaining a closed medication system.

Should needleless caps be changed before drawing blood samples?

Mathew, Alice, et al. “Central catheter blood sampling: the impact of changing the needleless caps prior to collection.” Journal of infusion nursing 32.4 (2009):212-218.
This study of 91 patients compared 3 methods of blood draws (old cap (existing cap), new cap (replacing old cap with a sterile one), and peripheral methods).  Nine false positive cases of bacteremia were identified using the old cap. Researchers recommending changing the cap before drawing culture samples.

 

Does changing needleless caps reduce the rate of infections?

Conflicting evidence exists on whether changing needleless caps reduces the rate of infections.

Do, A N, et al. “Bloodstream infection associated with needleless device use and the importance of infection-control practices in the home health care setting.” The Journal of infectious diseases 179.2 (1999):442-448.
Cohort study found that rate of bloodstream infections (BSIs) rate “decreased as the frequency of changing the needleless device end cap increased from once weekly up to every 2 days, suggesting that the mechanism for BSI may involve contamination from the end cap.”

McDonald, L C, S N NBanerjee, and W R RJarvis. “Line-associated bloodstream infections in pediatric intensive-care-unit patients associated with a needleless device and intermittent intravenous therapy.” Infection control and hospital epidemiology 19.10 (1998):772-777.
Bloodstream infection (BSI) rates increased in patients receiving “intermittent (vs continuous) intravenous therapy through one or more lumens. The IVAC device valvecomponent was replaced every 6 days, and the endcap used to cover the valve (when connected to an unused lumen) was replaced every 24 hours or after each access. The BSI rate returned to baseline after institution of a policy to replace the entire IVAC device, valve, and endcap every 24 hours.”

Danzig, L E, et al. “Bloodstream infections associated with a needleless intravenous infusion system in patients receiving home infusion therapy.” JAMA: the Journal of the American Medical Association 273.23 (1995):1862-1864.
Researchers conducted case-control and retrospective cohort studies. Data found that needleless device used for total parenteral nutrition and intralipid therapy (TPN/IL) “was associated with increased risk of BSI when injection caps were changed every 7 days.”

What evidence exists regarding femoral nerve block in joint surgery (hip,knee) and length of hospital stay?

Crowley, Conor, et al. “Impact of regional and local anaesthetics on length of stay in knee arthroplasty.” ANZ journal of surgery 82.4 (2012):207-214.

Systematic review: According to Crowley’s systematic review, 23 studies  using CONSORT 2001, (consolidated standards of reporting trials), were identified.  There were deficiencies in these studies as far sample size calculation and randomization concerning under reporting of blinding.  Neither  regional and local anesthesia  nor epidural and femoral nerve block has reduced hospital length of stay.

RCTs published after the review

Ward, James P, et al. “Are femoral nerve blocks effective for early postoperative pain management after hip arthroscopy?.” Arthroscopy 28.8 (2012):1064-1069.
shed after the Crowley article based on a small sample size of 36 subjects, concludes that based on all criteria the femoral nerve block is a good  alternative to routine narcotic pain medication for hip arthroplasty.

Spangehl MJ, et al. The Chitranjan Ranawat Award: Periarticular Injections and Femoral Sciatic Blocks Provide Similar Pain Relief After TKA: A Randomized Clinical Trial. Clin Orthop Relat Res 473.1 (2015 Jan):45-53.
160 patients undergoing knee arthoplasty received either femoral block or periarticular injection (PAI). LOS was 2.44 days for the PAI group and 2.84 days for the femoral block group.

Mahadevan D, et al. Combined femoral and sciatic nerve block vs combined femoral and periarticular infiltration in total knee arthroplasty: a randomized controlled trial. J Arthroplasty. 2012 Dec;27(10):1806-11.
Fifty-two patients undergoing total knee arthroplasty all received femoral nerve block.  They were randomized to also receive either sciatic block or periarticular injection.  LOS was 5.5 v. 6 days.

Are there methods that are effective at reducing nursing staff response time to patient call lights/bed alarms?

A search of PubMed, CINAHL, and ECRI (a quality and risk management resource) for combinations of these terms:
Call lights, call buttons, intercoms, stimuli
Patients, beds, rooms
Nurses, nursing
Response time, reaction time, attention
(call lights OR call buttons OR alarms) AND (patients OR beds OR rooms) AND (nurses OR nursing) AND (response time OR reaction time)…identified many articles about reducing the rate of call light use by implementing hourly/intentional/comfort rounding, as well as the association between call light use and falls. Below are a couple of references that explore how psychological factors may be associated with response time.

Kalisch BJ, et al. Nursing teamwork and time to respond to call lights: an exploratory study. Rev Lat Am Enfermagem. 2013 Jan-Feb;21 Spec No:242-9.

Tzeng HM. Perspectives of staff nurses toward patient- and family-initiated call light usage and response time to call lights. Appl Nurs Res. 2011 Feb;24(1):59-63. doi: 10.1016/j.apnr.2009.03.003. Epub 2009 Jul 9.

A Google search for no pass zone patient call lights identified several hospitals that have rolled out campaigns with this name, but there doesn’t seem to be anything in the traditional published literature about them. Here is information from a couple of hospitals in case you want to contact them directly for additional information.

http://nursing.advanceweb.com/News/Regional-News/Bronx-NY-Montefiore-Establishes-No-Passing-Zone.aspx

http://healthleadersmedia.com/content/NRS-250810/Nurses-Find-Simple-Ways-to-Improve-Satisfaction##

http://1199seiubenefits.org/wp-content/uploads/2012/01/Mt.-Sinai-Powerpoint.pdf

This question seems to be similar to alert fatigue with use of alerts in clinical systems. After browsing some of those references in PubMed, I applied the subject headings
(“Human engineering”[mesh] OR “Hospital communication systems”[mesh]) AND (“Reaction time”[mesh] OR “time factors”[mesh]) AND nurses AND (falls OR patient satisfaction)
The most relevant reference in this search is below. It discusses use of a different technology.
Guarascio-Howard L. Examination of wireless technology to improve nurse communication, response time to bed alarms, and patient safety. HERD. 2011 Winter;4(2):109-20.