Effectiveness and uses of Chlorhexidine Gluconate (CHG)

Skin preparation in the hand surgery clinic: A survey of Canadian plastic surgeons and a pilot study of a new technique. (2018). Canadian Journal of Infection Control, 33(2), 102.

Randomized, Prospective Study of the Order of Preoperative Preparation Solutions for Patients Undergoing Foot and Ankle Orthopedic Surgery. (2016). Foot & Ankle International /, 37(5), 478.

Reducing Mediastinitis after Sternotomy with Combined Chlorhexidine-Isopropyl Alcohol Skin Disinfection: Analysis of 3,000 Patients. (2016). Surgical Infections., 17(5), 552.

Reducing the risk of surgical site infections: Does chlorhexidine gluconate provide a risk reduction benefit? (2013). American Journal of Infection Control : Applied Epidemiology in Health Care Settings and the Community, 41(S5), S49.

Chlorhexidine is a better antiseptic than povidone iodine and sodium hypochlorite because of its substantive effect. (2013). American Journal of Infection Control : Applied Epidemiology in Health Care Settings and the Community, 41(7), 634.

BNurs. (2019). Antimicrobial-resistant bacteria (AMRB): Chlorhexidine Gluconate Body Washing Intensive Care (ICU) Settings

Nnaji. (2019). Surgical Site Infections: Intensive Care and Chlorhexidine Gluconate Bathing.

Manuel. (2018). Bloodstream Infections (Pediatrics): Chlorhexidine Gluconate Bathing.

Moola. (2018). Multidrug-Resistant Organisms: Chlorhexidine Gluconate Bathing.

Moola. (2018). Central Line-Associated Bloodstream Infections: Chlorhexidine Gluconate Bathing.

PubMed Search for additional literature on CHG usage

(((Chlorhexidine Gluconate OR chg)) AND (use or usage or uses)) AND procedure*

https://www.ncbi.nlm.nih.gov/pubmed?otool=emorylib

Compliance and education on using Chlorhexidine Gluconate (CHG) to prevent CLASBI’s

Chlorhexidine Bed-Bath Improves CLABSI: A Meta-Analysis. (2017). Journal of Nursing, 64(4), 71.

A comparative evaluation of antimicrobial coated versus nonantimicrobial coated peripherally inserted central catheters on associated outcomes: A randomized controlled trial. (2016). American Journal of Infection Control : Applied Epidemiology in Health Care Settings and the Community, 44(6), 636.

Frost, S. A., Hou, Y. C., Lombardo, L., Metcalfe, L., Lynch, J. M., Hunt, L., Alexandrou, E., Brennan, K., Sanchez, D., Aneman, A., & Christensen, M. (2018). Evidence for the effectiveness of chlorhexidine bathing and health care-associated infections among adult intensive care patients: a trial sequential meta-analysis. BMC Infectious Diseases, 18(1)
Chlorhexidine bathing and health care-associated infections among adult intensive care patients: A systematic review and meta-analysis. (2016). Critical Care : The Official Journal of the Critical Care Forum., 20, 379.

You get back what you give: Decreased hospital infections with improvement in CHG bathing, a mathematical modeling and cost analysis. (2019). American Journal of Infection Control : Applied Epidemiology in Health Care Settings and the Community, 47(12), 1471.

Chlorhexidine gluconate or polyhexamethylene biguanide disc dressing to reduce the incidence of central-line-associated bloodstream infection: A feasibility randomized controlled trial (the CLABSI trial). (2017). The Journal of Hospital Infection., 96(3), 223.

Central Line-Associated Bloodstream Infections: Chlorhexidine Gluconate Bathing. Moola, Sandeep [BDS MHSM (Hons) MPhil PhD]. [Evidence Summaries] AN: JBI9252
Year of Publication 2018

Bloodstream Infections (Pediatrics): Chlorhexidine Gluconate Bathing. Manuel, Beatriz [MD, MHPE, PhD candidate]. [Evidence Summaries] AN: JBI9364
Year of Publication 2018

Bore/Catheter Size and Catheter Associated Urinary Tract Infections (CAUTIs)

PICO question: Is there an association between inserting the smallest bore indwelling urinary catheter and a decreased CAUTI (catheter associated urinary tract infection) rate? Nurse was “looking for evidence-based practice, guideline, high level of evidence to support question.”

Here’s how to access a collection of 7 articles in PubMed.
a. Go to the Woodruff Health Sciences Center Library homepage (http://health.library.emory.edu)
b. Click on PubMed.
c. Then copy and paste the following link into your browser:
https://www-ncbi-nlm-nih-gov.proxy.library.emory.edu/sites/myncbi/1HMKnKhQm_d5i/collections/59174578/public/
d. The references will appear in PubMed. Click on a reference and you will see a Find it at Emory on the right side of the page which will provide links to full text within Emory University’s licensed resources. Emory Healthcare staff may send citations of needed articles they are unable to access to Ask a Librarian; a library staff person will request the article(s) from an outside library and email them to the EHC staff person upon arrival

Here’s notes about items in the collection.

Table 3 in the 2017 systematic review by Meddings et al states for catheter size, “The smallest bore catheter possible with consistent good drainage is recommended to avoid black neck and urethral mucosa trauma.” The two items it cites by Godfrey and Gould are in the PubMed collection.

Table 3 in article by Gao et al. states simply, “Choose a urethral catheter of the right size and right material, based on the patient’s age, sex, and urethral condition, among other characteristics” without any citing any evidence.

The entry for Catheter-associated Urinary Tract Infection (CAUTI) in DynaMed states, “consider using smallest bore catheter possible, with good drainage, to minimize bladder neck and urethral trauma unless not appropriate clinically” and cites and annotates the following guidelines by Gould and Lo that are in the PubMed collection.

Centers for Disease Control and Prevention Healthcare Infection Control Practices Advisory Committee (CDC HICPAC) recommendation grading system
• Category IA – strong recommendation supported by high- to moderate-quality evidence suggesting net clinical benefits or harms
• Category IB – strong recommendation supported by low-quality evidence suggesting net clinical benefits or harms or an accepted practice (for example, aseptic technique) supported by low- to very low-quality evidence
• Category IC – strong recommendation required by state or federal regulation
• Category II – weak recommendation supported by any quality evidence suggesting a trade-off between clinical benefits and harms
• No recommendation/unresolved issue – unresolved issue for which there is low- to very low-quality evidence with uncertain trade-offs between benefits and harms
• Reference – CDC HICPAC guideline on prevention of catheter-associated urinary tract infections

Society for Healthcare Epidemiology of America/Infectious Diseases Society of America (SHEA/IDSA) quality of evidence grades
• Grade I – high-quality evidence
o highly confident that true effect lies close to that of estimated size and direction of effect
o wide range of studies with no major limitations, little variation between studies, and summary estimate has a narrow confidence interval
o true effect is likely to be close to estimated size and direction of the effect, but there is a possibility that it is substantially different
• Grade II – moderate-quality evidence
o only a few studies and some have limitations but not major flaws
o some variation between studies, or the confidence interval of the summary estimate is wide
o true effect may be substantially different from estimated size and direction of the effect
• Grade III – low-quality evidence
o when supporting studies have major flaws, important variation between studies, the confidence interval of the summary estimate is very wide
o no rigorous studies, only expert consensus
• Reference – SHEA/IDSA practice recommendations on strategies to prevent catheter-associated urinary tract infections in acute care hospitals

Here are two of the search strings I used. I skimmed the most recent five years and did not include choose articles that studied only pediatric populations.

(CAUTI OR CAUTIs OR CA-UTI OR CA-UTIs OR catheter associated urinary tract infection OR catheter associated urinary tract infections OR catheter-associated urinary tract infection OR catheter-associated urinary tract infections) AND (small OR smaller OR smallest OR large OR larger OR largest OR size OR sizes OR bore OR bores OR caliber OR calibers)

(bundle OR bundles OR multipronged OR 6-c OR 6c OR toolkit OR toolkits) AND (CAUTI OR CAUTIs OR CA-UTI OR CA-UTIs OR catheter associated urinary tract infection OR catheter associated urinary tract infections OR catheter-associated urinary tract infection OR catheter-associated urinary tract infections) AND (lower OR lowers OR lowered OR lowering OR decrease OR decreases OR decreased OR decreasing OR reduce OR reduces OR reduced OR reducing OR reduction OR reductions OR improve OR improves OR improved OR improving OR improvement OR improvements OR better OR best)

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Important message for Emory Decatur Nurses. The links will not work for you. To access these articles contact the Emory Decatur Library:

Emory Decatur Hospital
Jessica Callaway (Jessica.callaway@emoryhealthcare.org)
404.501.1628

What is the evidence for using tap water vs sterile water to flush feeding tubes?

The type of feeding tube seems to determine whether water or sterile water should be used.

Below are several results from the Joanna Briggs Institute (JBI) database, which includes “selected clinical topics in evidence based recommended practices, evidence summaries, best practice information sheets, systematic reviews, and more.” You should have access to JBI and to the documents below using your Healthcare ID and password.

Nasoenteric Tube Feeding
Enteral Tube Feeding
Percutaneous Endoscopic Gastrostomy: Tube Blockage

For additional results, access JBI and search for feeding tube and limit to the types of evidence you seek.

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Important message for Emory Decatur Nurses.

The links will not work for you. To access these articles contact the Emory Decatur Library:

Emory Decatur Hospital
Jessica Callaway (Jessica.callaway@emoryhealthcare.org)
404.501.1628

Falls prevention and mobility promotion

These articles are about falls prevention and mobility promotion. Non-hospitalized adults are included to maximize the number of helpful articles.
Two noteworthy articles

 

Growdon ME, Shorr RI, Inouye SK. The tension between promoting mobility and preventing falls in the hospitalJAMA Intern Med. 2017 Jun 1;177(6):759-760. doi: 10.1001/jamainternmed.2017.0840.

Sinha SK, Detsky AS. Measure, promote, and reward mobility to prevent falls in older patientsJAMA. 2012 Dec 26;308(24):2573-4. doi: 10.1001/jama.2012.68313. No abstract available.

Here’s how to access the full collection of 14 items in PubMed.

a. Go to the Woodruff Health Sciences Center Library homepage (http://health.library.emory.edu)
b. Click on PubMed.
c. Then paste the following link into your browser:
https://www.ncbi.nlm.nih.gov/sites/myncbi/1HMKnKhQm_d5i/collections/58770766/public/
d. The references will appear in PubMed. Click on a reference and you will see a Find it at Emory on the right side of the page which will provide links to full text within Emory University’s licensed resources. Emory Healthcare staff may send citations of needed articles they are unable to access to Ask a Librarian; a library staff person will request the article(s) from an outside library and email them to the EHC staff person upon arrival.

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Important message for Emory Decatur Nurses. The links will not work for you. To access these articles contact the Emory Decatur Library:

Emory Decatur Hospital
Jessica Callaway (Jessica.callaway@emoryhealthcare.org
404.501.1628

Prevention and Treatment of Pressure Ulcers: Clinical Practice Guideline

Prevention and Treatment of Pressure Ulcers: Clinical Practice Guideline

Developed by the National Pressure Ulcer Advisory Panel, the European Pressure Ulcer Advisory Panel and the Pan Pacific Pressure Injury Alliance, this guideline presents a comprehensive review and appraisal of the best available evidence to the assessment, diagnosis, prevention and treatment of pressure ulcers. This is a general guide to appropriate clinical practice, to be implemented by qualified health professionals subject to their clinical judgment and the patient’s personal preferences and available resources.

If a patient has both an arterial sheath and a venous sheath, which should be removed first?

Experts state that the arterial sheet should be removed first on these two webpages within the Cath Lab Digest website.

https://www.cathlabdigest.com/articles/Correct-Way-Pull-Sheath

https://www.cathlabdigest.com/articles/Ask-Clinical-Instructor-A-QA-column-those-new-cath-lab-27

Following is a section in a cardiac cath book that also states that the arterial sheath should be removed first. The citation for the book and a link to access it follows the quote. The path to click to get to the particular passage in the book is also included after the quote.

“Control of the Puncture Site Following Sheath Removal
Originally, standard groin management required the effect of heparin to wear off or be reversed by protamine to an ACT <160 seconds before the arterial catheter and sheath were removed and manual pressure applied, except in the case of bivalirudin as mentioned above. Manual pressure method is best applied using three fingers of the left hand that are positioned sequentially up the femoral artery beginning at the skin puncture. With the fingers in this position, there should be no ongoing bleeding into the soft tissues or through the skin puncture, and it should be possible to apply sufficient pressure to obliterate the pedal pulses and then release just enough pressure to allow them to barely return. Pressure is then gradually reduced over the next 10 to 15 minutes, at the end of which time pressure is removed completely. The venous sheath is usually removed 5 minutes after compression of the arterial puncture has begun, with gentle pressure applied over the venous puncture using the right hand. To avoid tying up the catheterization laboratory during this period, patients were usually taken to a special holding room in the catheterization laboratory or back to their hospital beds before the sheaths were removed. If such relocation is to be performed prior to sheath removal, it is important that the sheaths are secured in place (suture, or at least tape) to prevent them being pulled out during transport.
When procedures are performed using larger arterial sheaths or with thrombolytic agents or IIb/IIIa receptor blockers, more prolonged (30- to 45-min) compression is typically required. To avoid fatigue of the operator or other laboratory personnel performing compression, occasionally a mechanical device (Compressar [Applied Vascular Dynamics, Portland, OR], The Clamp Ease device [Pressure Products Inc., Rancho Palos Verdes, California] or FemoStop [Radi Medical, Wilmington, MA]) can be used to apply similar local pressure. These devices can be equally or even more effective in prolonged holds,22 but are uncomfortable for the patients and human supervision is required while in place; hence manual compression is preferred for removal of smaller (6F) sheaths or in patients with peripheral vascular disease or prior peripheral grafting surgery where occlusive compression or flow restriction might cause arterial occlusion. In every case, however, it should be emphasized that a trained person must be in attendance throughout the compression to ensure that the device is providing adequate control of puncture site bleeding and is not compromising distal perfusion.”
From Grossman and Baim’s Cardiac Catheterization, Angiography, and Intervention; editor, Mauro Moscucci, MD, MBA, professor of medicine, chairman, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida. — Eighth edition. Copyright 2014 (new edition will be coming out in 2020). Main page for book > Table of Contents > Section II – Basic Techniques > 6 – Percutaneous Approach, Including Transseptal and Apical Puncture > CATHETERIZATION VIA THE FEMORAL ARTERY AND VEIN > Control of the Puncture Site Following Sheath Removal
Link to book: https://tinyurl.com/y2hqn6wf

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Important message for Emory Decatur Nurses. The link to the book will not work for you. To access the book contact the Emory Decatur Library:

Emory Decatur Hospital
Jessica Callaway (Jessica.callaway@emoryhealthcare.org
404.501.1628