Emory Authors: Metabolomic Associations With Fatigue and Physical Function in Children With Cancer: A Pilot Study

“Fatigue is the most commonly reported symptom in children and adolescents during and after treatment for cancer. Fatigue is associated with decreased quality of life and may contribute to decreased physical function and impede normal childhood development. Currently, the only validated way to measure fatigue is through collection of self-reported data which may not be feasible for all children, specifically younger or sicker children, or those with lower reading levels. Proxy (i.e., parent) reports are often used as substitute measures but may not replace a child’s own report. In the precision medicine era, identifying biomarkers for fatigue would be beneficial in screening for and applying interventions to address this common symptom. A metabolomic approach to unraveling symptom experiences is promising as it allows for investigation of multiple metabolites and pathways at once and can provide insight into the physiological status of an individual at any one point in time.”

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Orthostatic Blood Pressure: Best Practices

“Measurement of blood pressure changes associated with postural change is a common parameter used in a select group of ED patients as an adjunct in the assessment of volume status, hemodynamic stability, and medication toxicity. Orthostatic hypotension has been defined by a consensus statement developed by the American Academy of Neurology and American Autonomic Society as a decrease in systolic blood pressure of > 20 mm Hg or a diastolic drop > 10 mm Hg within 3 min of going from a supine to a standing position” (Guss)

Guss

Guss, D. A., Abdelnur, D., & Hemingway, T. J. (2008). The impact of arm position on the measurement of orthostatic blood pressure. The Journal of emergency medicine, 34(4), 377-382.

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If a patient has both an arterial sheath and a venous sheath, which should be removed first?

Experts state that the arterial sheet should be removed first on these two webpages within the Cath Lab Digest website.

https://www.cathlabdigest.com/articles/Correct-Way-Pull-Sheath

https://www.cathlabdigest.com/articles/Ask-Clinical-Instructor-A-QA-column-those-new-cath-lab-27

Following is a section in a cardiac cath book that also states that the arterial sheath should be removed first. The citation for the book and a link to access it follows the quote. The path to click to get to the particular passage in the book is also included after the quote.

“Control of the Puncture Site Following Sheath Removal
Originally, standard groin management required the effect of heparin to wear off or be reversed by protamine to an ACT <160 seconds before the arterial catheter and sheath were removed and manual pressure applied, except in the case of bivalirudin as mentioned above. Manual pressure method is best applied using three fingers of the left hand that are positioned sequentially up the femoral artery beginning at the skin puncture. With the fingers in this position, there should be no ongoing bleeding into the soft tissues or through the skin puncture, and it should be possible to apply sufficient pressure to obliterate the pedal pulses and then release just enough pressure to allow them to barely return. Pressure is then gradually reduced over the next 10 to 15 minutes, at the end of which time pressure is removed completely. The venous sheath is usually removed 5 minutes after compression of the arterial puncture has begun, with gentle pressure applied over the venous puncture using the right hand. To avoid tying up the catheterization laboratory during this period, patients were usually taken to a special holding room in the catheterization laboratory or back to their hospital beds before the sheaths were removed. If such relocation is to be performed prior to sheath removal, it is important that the sheaths are secured in place (suture, or at least tape) to prevent them being pulled out during transport.
When procedures are performed using larger arterial sheaths or with thrombolytic agents or IIb/IIIa receptor blockers, more prolonged (30- to 45-min) compression is typically required. To avoid fatigue of the operator or other laboratory personnel performing compression, occasionally a mechanical device (Compressar [Applied Vascular Dynamics, Portland, OR], The Clamp Ease device [Pressure Products Inc., Rancho Palos Verdes, California] or FemoStop [Radi Medical, Wilmington, MA]) can be used to apply similar local pressure. These devices can be equally or even more effective in prolonged holds,22 but are uncomfortable for the patients and human supervision is required while in place; hence manual compression is preferred for removal of smaller (6F) sheaths or in patients with peripheral vascular disease or prior peripheral grafting surgery where occlusive compression or flow restriction might cause arterial occlusion. In every case, however, it should be emphasized that a trained person must be in attendance throughout the compression to ensure that the device is providing adequate control of puncture site bleeding and is not compromising distal perfusion.”
From Grossman and Baim’s Cardiac Catheterization, Angiography, and Intervention; editor, Mauro Moscucci, MD, MBA, professor of medicine, chairman, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida. — Eighth edition. Copyright 2014 (new edition will be coming out in 2020). Main page for book > Table of Contents > Section II – Basic Techniques > 6 – Percutaneous Approach, Including Transseptal and Apical Puncture > CATHETERIZATION VIA THE FEMORAL ARTERY AND VEIN > Control of the Puncture Site Following Sheath Removal
Link to book: https://tinyurl.com/y2hqn6wf

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Important message for Emory Decatur Nurses. The link to the book will not work for you. To access the book contact the Emory Decatur Library:

Emory Decatur Hospital
Jessica Callaway (Jessica.callaway@emoryhealthcare.org
404.501.1628

Support groups for heart failure inpatients

Go to the HSCL webpage: http://health.library.emory.edu/
Click on PubMed.
Copy this link into your browser and hit enter to see a collection of 5 useful articles: https://www.ncbi.nlm.nih.gov/sites/myncbi/1HMKnKhQm_d5i/collections/51442710/public
The list of references will appear in PubMed.
By using these instructions, you will be able to click on a reference and see the Find it at Emory button which will lead to full text if available; a login will be required. If online full text is not available and you are an Emory Healthcare employee, send citation(s) to Ask a Librarian for staff to get the article for you.

Here is the search technique: support groups AND heart failure. One citation was kept because the article cites a dissertation that may be useful.

Role of nurse practitioners in cardiology

You can run a PubMed search by cutting and pasting the following into the PubMed search field:

(((“Women’s Health”[Mesh] OR (cardiology OR cardiac))) AND “Nurse Practitioners”[Majr]) AND “Nurse’s Role”[Mesh]

Selected resources:

The evolution of specialists in women’s health care across the lifespan: women’s health nurse practitioners

The past, present, and future of the advanced practice role in women’s healthcare.

Literature review of the impact of nurse practitioners in critical care services.

Optimal management of outpatients with heart failure using advanced practice nurses in a hospital-based heart failure center.

Patients with heart failure in primary health care: effects of a nurse-led intervention on health-related quality of life and depression.

Communicating about evidence-based practice in patient care

Welcome. This blog facilitates communication on issues of evidence-based practice by Emory Healthcare Nursing Quality Initiatives teams. Questions posed by the teams and information to address those questions will be documented in these posts.