What is the reported incidence of central line blood stream infections based on central line device type (PICC, tunneled line, etc.)?

Maki DG, et al.  The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies.   Mayo Clin Proc. 2006 Sep;81(9):1159-71.

Included English-language articles of prospective studies of adults published between January 1, 1966, and July 1, 2005, identified in MEDLINE.

Tables 3 summarizes data for various types of catheters and reports incidence by infections per 1,000 catheter days.

What are defined best practices in the literature to perform a central line dressing change?

Marschall J, et al.  Strategies to prevent central line-associated bloodstream infections in acute care hospitals.  Infect Control Hosp Epidemiol. 2008;29(Suppl 1):S22-S30.

For nontunneled CVCs in adults

Transparent dressings:  change and disinfect site with chlorhexidine‐based antiseptic every 5‐7 days or more frequently for soiled, loose, or damp dressing

Gauze dressings:  Change every 2 days or more frequently for soiled, loose, or damp dressing

Evidence for this practice came from ≥ 1 properly randomized, controlled trial and evidence considered to be good to support a recommendation for use from the Society for Healthcare Epidemiology of America.

Detailed instructions for changing a dressing are found within the following review article.

Macklin D. Catheter management. Semin Oncol Nurs. 2010;26(2):113-120.

Reviewed and updated 4/11/2014 ldt

Are occlusive dressings effective for preventing central line infections?

Webster J, et al. Gauze and tape and transparent polyurethane dressings for central venous catheters. Cochrane Database Syst Rev. 2011 Nov 9;(11):CD003827.
Reviewed six studies; “four compared gauze and tape with transparent polyurethane dressings (total participants – 33) and two compared different transparent polyurethane dressings (total participants = 126).” A four-fold increase in CLABSIs was found with polyurethane dressings. However, because of a risk of bias and wide confidence intervals the “true effect could be as small as 2% or as high as 17-fold.”

McCann M, Moore ZE. Interventions for preventing infectious complications in haemodialysis patients with central venous catheters. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD006894.
Includes review of one study (n=58) on use of polyurethane transparent dressings and gauze in hemodialysis patients. There was no statistically significant difference in incidence of central line site infection or central-line associated bacteremia between gauze and polyurethane.

Gillies D, et al. Central venous catheter dressings: a systematic review. J Adv Nurs. 2003 Dec;44(6):623-32.
Searched Cochrane databases, Medline, CINAHL, and CancerLit.  Identified and reviewed 8 studies that evaluate various dressings in the incidence of CVC-related infection and in catheter-related sepsis in hospitalized patients.
RESULTS: Studies included comparison of gauze/tape v. Opsite IV 3000; Opsite v. Opsite IV 3000; Tegaderm v. Opsite IV 3000; Tegaderm v. Opsite.
In the 6 studies with pooled data, odds ratios did not favor either group for incidence of infection. Review was limited in that all studies had small populations.
See Table 4 for summary of meta-analysis.

Hoffman K, et al. Transparent polyurethane film as an intravenous catheter dressing. A meta-analysis of the infection risks. JAMA. 1992 Apr 15;267(15):2072-6
This is a systematic review of 7 studies, but a couple of the studies compared gauze plus a topical antiseptic preparation to occlusive dressing without the topical.

Reviewed and updated 4/24/2014 ldt

Communicating about evidence-based practice in patient care

Welcome. This blog facilitates communication on issues of evidence-based practice by Emory Healthcare Nursing Quality Initiatives teams. Questions posed by the teams and information to address those questions will be documented in these posts.