What is the recent evidence on whether closed catheter systems prevent catheter-associated bloodstream infections (CLABSIs)?

Ishizuka, Mitsuru, et al. “Needleless closed system does not reduce central venous catheter-related bloodstream infection: a retrospective study.” International surgery 98.1 (2013):88-93.

Newman, Nitza, et al. “Central venous catheter-associated bloodstream infections.” Pediatric blood & cancer 59.2 (2012):410-414.

Ellger, B, et al. “Non-return valves do not prevent backflow and bacterial contamination of intravenous infusions.” Journal of hospital infection 78.1 (2011):31-35.

Graves, Nicholas, Adrian GBarnett, and Victor DRosenthal. “Open versus closed IV infusion systems: a state based model to predict risk of catheter associated blood stream infections.” BMJ open 1.2 (2011):e000188-e000188.

Maki, Dennis G, et al. “Impact of switching from an open to a closed infusion system on rates of central line-associated bloodstream infection: a meta-analysis of time-sequence cohort studies in 4 countries.” Infection control and hospital epidemiology 32.1 (2011):50-58.

McAfee, Nancy, et al. “A continuous quality improvement project to decrease hemodialysis catheter infections in pediatric patients: use of a closed luer-lock access cap.” Nephrology Nursing Journal 37.5 (2010):541-4.

Jarvis, William R, et al. “Health care-associated bloodstream infections associated with negative- or positive-pressure or displacement mechanical valve needleless connectors.” Clinical infectious diseases 49.12 (2009):1821-1827.

Ishizuka, Mitsuru, et al. “Valve system does not reduce the catheter-related bloodstream infection.” Journal of investigative surgery 22.6 (2009):430-434.

Vilins, Margarete, et al. “Rate and time to develop first central line-associated bloodstream infections when comparing open and closed infusion containers in a Brazilian Hospital.” The Brazilian journal of infectious diseases 13.5 (2009):335-340.

Ivy, D D, et al. “Closed-hub systems with protected connections and the reduction of risk of catheter-related bloodstream infection in pediatric patients receiving intravenous prostanoid therapy for pulmonary hypertension.” Infection control and hospital epidemiology 30.9 (2009):823-829.

Franzetti, F, et al. “Impact on rates and time to first central vascular-associated bloodstream infection when switching from open to closed intravenous infusion containers in a hospital setting.” Epidemiology and Infection 137.7 (2009):1041-1048.

Blake, Molly. “Update: Catheter-related bloodstream infection rates in relation to clinical practice and needleless device type.” The Canadian journal of infection control 23.3 (2008):156-60, 162.

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About Lisa

I have been a Clinical Informationist (aka Medical Librarian) for Emory University since September 2013. Prior to that, I was a Medical Librarian for Lincoln Memorial University (LMU) from March 2007 to August 2013 and served its DeBusk College of Osteopathic Medicine (LMU-DCOM), Caylor School of Nursing, and allied health programs. From January 2002 - March 2007, I served the Medical Assisting (MA), Occupational Therapy Assistant, Physical Therapy Assistant, Radiologic Technologist, and Nursing programs at South College in Knoxville, Tennessee. I graduated from The University of Tennessee School of Information Sciences with a Master of Science degree in December 2000. Received a Educational Specialist (EdS) degree in Educational Administration and Supervision with a higher education focus in August 2010 from LMU.

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