Bottom line: For patients undergoing orthopedic procedures, there is some evidence suggesting an association between perioperative HbA1c levels and complications involvoing the surgical site.
PubMed search: (orthopedic procedures OR orthopedic surgery) AND (hemoglobin A1c OR hba1c)
The following references from the search results provided data on HbA1c in patients undergoing orthopedic procedures.
Jamsen (2010): prospective cohort study of 1565 elective knee surgeries for which preoperative plasma glucose was recorded. Patients followed 20 months. Mean HbA1c
Younger (2009): Case-control study matching 21 patients with failed transmetatarsal amputation (TMA) with 21 successful TMAs. HbA1c was the factor most closely associated with success of the TMA.
Marchant (2009): Retrospective study of >1 million patients undergoing joint replacement surgery 1988-2005 as recorded in the Nationwide Inpatient Sample. Patients with controlled diabetes mellitus (determined by combination of patient-measured blood glucose and HbA1c) had increased risk of wound infection (adjusted odds ratio = 2.28 compared to patients with controlled diabetes mellitus.
Lamloum (2009): Retrospective study of 318 consecutive diabetic patients undergoing surgery at an orthopedic hospital. Table 3 compares rates of surgical site infections (SSI) for patients with HbA1c < 7.0 compared to rate for patients with HbA1c ≥ 7.0. High HbA1c was associated with higher rate of SSI
Reviewed by John Nemeth 4/14