Bottom line:  The implications of cytoreductive surgery and HIPEC on postoperative care include prevention of infection, nutritional support and support and education for devices or other procedures that often accompany this procedure.

Dunn D. Surgical Treatment of Patients With Peritoneal Surface Malignancy: Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy.  J Wound, Ostomy and Continence Nurs. 2010; 37(4): 379-85.
Review of cytoreductive surgery and HIPEC, as well as factors to consider in providing postoperative care to these patients, including prevention of surgical site infection, maintenance and education for patient/family on devices, such as drains, nutritional support, and pain control.